New findings from a single-cell RNA sequencing analysis of cervical cancer tissues reveal key factors involved in cervical cancer initiation and progression.
The study by Chao Liu and colleagues, published in January in Science Advances, provides great insight into the transcriptional programs underlying each stage of cervical squamous cell carcinoma (CESC). The researchers sequenced more than 75,000 cells isolated from human cancer tissues at various stages of malignancy. From here, they could observe the trajectory of cervical epithelial cells and the correlations between the abundance of specific myeloid, lymphoid and endothelial cell populations and CESC progression.
This is a fascinating study and a very interesting read: https://lnkd.in/eMAYu9nr
Well done to all those involved in this impactful study!